Strike Witches is a mixed-media project originally created by Humikane Shimada via a series of magazine illustration columns. It was later adapted into two light novel series, three manga series, an anime OVA, a televised anime series and various video games. The story revolves around teenage girls who use machines equipped to their legs to do aerial combat. The OVA preview episode was released on January 1, 2007. The televised anime series later aired between on July 3, 2008, and September 18, 2008. A second season aired between July 8, 2010 and September 23, 2010. A film adaptation was released on March 17, 2012. A third season and OVA has been announced.

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Set in an alternate Earth in the mid twentieth century, Strike Witches tells the story of a fight to protect the world using a combination of magic and technology in a fictional recreation of events occurring in World War II with the national armies joining forces to confront an overwhelming alien threat together instead of fighting among themselves. Most battles featured in the franchise are fictional recreations of real conflicts of that time, with the human army taking the role of the Allied Forces, and the Neuroi assuming the side of the Axis Powers.

The titular Strike Witches are young women with high magical potential who are recruited into military organizations around the world to fight against the enigmatic Neuroi, which began an invasion of unprecedented scale on human territory in 1939.

There are currently four games based on the Strike Witches franchise. While mainly based on the characters featured in the anime, characters from the two manga series also appear in some of the games. The first three Strike Witches games will have the same opening "private wing" by Yoko Ishida.

Strike Witches - Anata to Dekiru Koto - A Little Peaceful Days: is a visual novel title also developed by Russell Games for PlayStation 2, which was released on May 27, 2010. This adventure game features Amaki Suwa and Nishiki Nakajima. To the south of the base lies a deserted island where the Witches are conducting open-air exercises. However, when the carrier they are stationed on comes under surprise Neuroi attack, the Witches are left stranded. In the two weeks that it will take for reinforcements to arrive, the Witches decide to carry on with their maneuvers, as well as make sure they can survive.

The Limited Edition was released with a drama CD.